Mechanism of quinolone resistance in anaerobic bacteria
نویسندگان
چکیده
منابع مشابه
Mechanism of plasmid-mediated quinolone resistance.
Quinolones are potent antibacterial agents that specifically target bacterial DNA gyrase and topoisomerase IV. Widespread use of these agents has contributed to the rise of bacterial quinolone resistance. Previous studies have shown that quinolone resistance arises by mutations in chromosomal genes. Recently, a multiresistance plasmid was discovered that encodes transferable resistance to quino...
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Antibiotic-resistant anaerobic bacteria have become increasingly recognized as a confounding factor in the selection of therapeutic agents. The use of potent, broad-spectrum antibiotics as empirical therapy, along with appropriate adjunctive measures, has, in some ways, masked the magnitude of the antibiotic resistance problem that parallels that observed for nonanaerobic pathogens. The use of ...
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ژورنال
عنوان ژورنال: Clinical Microbiology and Infection
سال: 2003
ISSN: 1198-743X
DOI: 10.1046/j.1469-0691.2003.00725.x